Clinical and Molecular Characterization of Brazilian Patients Suspected to Have Lynch Syndrome.

Clinical and Molecular Characterization of Brazilian Patients Suspected to Have Lynch Syndrome.

Lynch syndrome (LS) accounts for 3-5% of all colorectal cancers (CRC) and is inherited in an autosomal dominant fashion. This syndrome is characterized by early CRC onset, high incidence of tumors in the ascending colon, excess of synchronous/metachronous tumors and extra-colonic tumors. Nowadays, L...

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Bibliographic Details
Main Authors: Felipe Carneiro da Silva, José Roberto de Oliveira Ferreira, Giovana Tardin Torrezan, Márcia Cristina Pena Figueiredo, Érika Maria Monteiro Santos, Wilson Toshihiko Nakagawa, Rafael Canfield Brianese, Ligia Petrolini de Oliveira, Maria Dirlei Begnani, Samuel Aguiar-Junior, Benedito Mauro Rossi, Fábio de Oliveira Ferreira, Dirce Maria Carraro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4593564?pdf=render

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http://europepmc.org/articles/PMC4593564?pdf=render

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