Genetically-encoded yellow fluorescent cAMP indicator with an expanded dynamic range for dual-color imaging.

Cyclic AMP is a ubiquitous second messenger, which mediates many cellular responses mainly initiated by activation of cell surface receptors. Various Förster resonance energy transfer-based ratiometric cAMP indicators have been created for monitoring the spatial and temporal dynamics of cAMP at the...

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Bibliographic Details
Main Authors: Haruki Odaka, Satoshi Arai, Takafumi Inoue, Tetsuya Kitaguchi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4069001?pdf=render