Synthesis of Phospholipid-Protein Conjugates as New Antigens for Autoimmune Antibodies

Synthesis of Phospholipid-Protein Conjugates as New Antigens for Autoimmune Antibodies

Copper(I)-catalyzed azide-alkyne cycloaddition, or CuAAC click chemistry, is an efficient method for bioconjugation aiming at chemical and biological applications. Herein, we demonstrate how the CuAAC method can provide novel phospholipid-protein conjugates with a high potential for the diagnostics...

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Bibliographic Details
Main Authors: Arindam Maity, Claudia Macaubas, Elizabeth Mellins, Kira Astakhova
Format: Article
Language:English
Published: MDPI AG 2015-06-01
Series:Molecules
Subjects:
CuAAC click chemistry
antiphospholipid syndrome
antigens
β2-glycoprotein I
phosphoethanolamine
prothrombin
Online Access:http://www.mdpi.com/1420-3049/20/6/10253

Internet

http://www.mdpi.com/1420-3049/20/6/10253

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