Dimeric and Multimeric DNA Aptamers for Highly Effective Protein Recognition

Dimeric and Multimeric DNA Aptamers for Highly Effective Protein Recognition

Multivalent interactions frequently occur in biological systems and typically provide higher binding affinity and selectivity in target recognition than when only monovalent interactions are operative. Thus, taking inspiration by nature, bivalent or multivalent nucleic acid aptamers recognizing a sp...

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Bibliographic Details
Main Authors: Claudia Riccardi, Ettore Napolitano, Domenica Musumeci, Daniela Montesarchio
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Molecules
Subjects:
aptamer
G-quadruplex
design
dimerization
multivalency
molecular recognition
Online Access:https://www.mdpi.com/1420-3049/25/22/5227

Internet

https://www.mdpi.com/1420-3049/25/22/5227

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