TiO2 Nanoparticles Caused DNA Damage in Lung and Extra-Pulmonary Organs Through ROS-Activated FOXO3a Signaling Pathway After Intratracheal Administration in Rats

TiO2 Nanoparticles Caused DNA Damage in Lung and Extra-Pulmonary Organs Through ROS-Activated FOXO3a Signaling Pathway After Intratracheal Administration in Rats

Bin Han1 ,* Zijie Pei2 ,* Lei Shi,3 Qian Wang,4 Chen Li,1 Boyuan Zhang,1 Xuan Su,1 Ning Zhang,1 Lixiao Zhou,1 Bo Zhao,5 Yujie Niu,3,6 Rong Zhang1,6 1Department of Toxicology, Hebei Medical University, Shijiazhuang 050017, Hebei, People’s Republic of China; 2Department of Pathology, Medical...

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Bibliographic Details
Main Authors: Han B, Pei Z, Shi L, Wang Q, Li C, Zhang B, Su X, Zhang N, Zhou L, Zhao B, Niu Y, Zhang R
Format: Article
Language:English
Published: Dove Medical Press 2020-08-01
Series:International Journal of Nanomedicine
Subjects:
nano-tio2
dna damage
pi3k/akt/foxo3a signaling pathway
dna repair，gadd45α/chk2/ xrcc1 signaling pathway
Online Access:https://www.dovepress.com/tio2-nanoparticles-caused-dna-damage-in-lung-and-extra-pulmonary-organ-peer-reviewed-article-IJN

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https://www.dovepress.com/tio2-nanoparticles-caused-dna-damage-in-lung-and-extra-pulmonary-organ-peer-reviewed-article-IJN

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