Lymphotoxin-alpha gene and risk of myocardial infarction in 6,928 cases and 2,712 controls in the ISIS case-control study.

Lymphotoxin-alpha gene and risk of myocardial infarction in 6,928 cases and 2,712 controls in the ISIS case-control study.

Lymphotoxin-alpha (LTA) is a pro-inflammatory cytokine that plays an important role in the immune system and local inflammatory response. LTA is expressed in atherosclerotic plaques and has been implicated in the pathogenesis of atherosclerosis and coronary heart disease (CHD). Polymorphisms in the...

Full description

Bibliographic Details
Main Authors: Robert Clarke, Peng Xu, Derrick Bennett, Sarah Lewington, Krina Zondervan, Sarah Parish, Alison Palmer, Sarah Clark, Lon Cardon, Richard Peto, Mark Lathrop, Rory Collins, International Study of Infarct Survival (ISIS) Collaborators
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-07-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC1487176?pdf=render

Internet

http://europepmc.org/articles/PMC1487176?pdf=render

Similar Items