Impaired Potentiation of Theta Oscillations During a Visual Cortical Plasticity Paradigm in Individuals With Schizophrenia

Long-term potentiation (LTP) is a form of experience-dependent synaptic plasticity mediated by glutamatergic transmission at N-methyl-D-aspartate receptors (NMDARs). Impaired neuroplasticity has been implicated in the pathophysiology of schizophrenia, possibly due to underlying NMDAR hypofunction. A...

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Bibliographic Details
Main Authors: Holly K. Hamilton, Brian J. Roach, Idil Cavus, Timothy J. Teyler, Wesley C. Clapp, Judith M. Ford, Erendiz Tarakci, John H. Krystal, Daniel H. Mathalon
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Psychiatry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2020.590567/full