Plasma and memory B cell responses targeting O-specific polysaccharide (OSP) are associated with protection against Vibrio cholerae O1 infection among household contacts of cholera patients in Bangladesh.

Plasma and memory B cell responses targeting O-specific polysaccharide (OSP) are associated with protection against Vibrio cholerae O1 infection among household contacts of cholera patients in Bangladesh.

BACKGROUND:The mediators of protection against cholera, a severe dehydrating illness of humans caused by Vibrio cholerae, are unknown. We have previously shown that plasma IgA as well as memory B IgG cells targeting lipopolysaccharide (LPS) of Vibrio cholerae O1 correlate with protection against V....

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Bibliographic Details
Main Authors: Amena Aktar, M Arifur Rahman, Sadia Afrin, Aklima Akter, Taher Uddin, Tahirah Yasmin, Md Israk Nur Sami, Pinki Dash, Sultana Rownok Jahan, Fahima Chowdhury, Ashraful I Khan, Regina C LaRocque, Richelle C Charles, Taufiqur Rahman Bhuiyan, Anjali Mandlik, Meagan Kelly, Pavol Kováč, Peng Xu, Stephen B Calderwood, Jason B Harris, Firdausi Qadri, Edward T Ryan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-04-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC5912711?pdf=render

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http://europepmc.org/articles/PMC5912711?pdf=render

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