Ectopic expression of MiR-125a inhibits the proliferation and metastasis of hepatocellular carcinoma by targeting MMP11 and VEGF.

BACKGROUND: Studies have been shown that miR-125a plays an important role in carcinogenesis, however, the role of miR-125a in hepatocellular carcinoma (HCC) remains elusive. METHODOLOGY/PRINCIPAL: Real time-PCR (qRT-PCR) was performed to test the significance of miR-125a in HCC. Ectopic expression o...

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Bibliographic Details
Main Authors: Qian Bi, Shanhong Tang, Lin Xia, Rui Du, Rui Fan, Liucun Gao, Jiang Jin, Shuhui Liang, Zheng Chen, Guanghui Xu, Yongzhan Nie, Kaichun Wu, Jie Liu, Yongquan Shi, Jie Ding, Daiming Fan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3387011?pdf=render