Ketamine/xylazine and barbiturates modulate microglial morphology and motility differently in a mouse model.

Microglia, the resident immune cells of the brain, are highly ramified and motile and their morphology is strongly linked to their function. Microglia constantly monitor the brain parenchyma and are crucial for maintaining brain homeostasis and fine-tuning neuronal networks. Besides affecting neuron...

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Bibliographic Details
Main Authors: Ines Hristovska, Franck Verdonk, Jean-Christophe Comte, Eileen S Tsai, Virginie Desestret, Jérôme Honnorat, Fabrice Chrétien, Olivier Pascual
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0236594