Targeting MALAT1 and miRNA-181a-5p for the intervention of acute lung injury/acute respiratory distress syndrome

Targeting MALAT1 and miRNA-181a-5p for the intervention of acute lung injury/acute respiratory distress syndrome

Abstract Background ALI/ARDS is a severe lung injury leading to refractory respiratory failure, accounting for high morbidity and mortality. However, therapeutic approaches are rather limited. Targeting long non-coding RNA MALAT1 and microRNA miR-181a-5p might be potential option for ALI/ARDS interv...

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Bibliographic Details
Main Authors: Yaling Liu, Xiaodong Wang, Peiying Li, Yanhua Zhao, Liqun Yang, Weifeng Yu, Hong Xie
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Respiratory Research
Subjects:
Acute lung injury
Lipopolysaccharide
Metastasis-associated lung adenocarcinoma transcript-1
miRNA-181a-5p
Factor associated suicide
Pro-inflammatory factor
Online Access:https://doi.org/10.1186/s12931-020-01578-8

Internet

https://doi.org/10.1186/s12931-020-01578-8

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