Increased Infiltration of Extra-Cardiac Cells in Myxomatous Valve Disease

Increased Infiltration of Extra-Cardiac Cells in Myxomatous Valve Disease

Mutations in the actin-binding gene Filamin-A have been linked to non-syndromic myxomatous valvular dystrophy and associated mitral valve prolapse. Previous studies by our group traced the adult valve defects back to developmental errors in valve interstitial cell-mediated extracellular matrix remod...

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Bibliographic Details
Main Authors: Kimberly Sauls, Katelynn Toomer, Katherine Williams, Amanda J. Johnson, Roger R. Markwald, Zoltan Hajdu, Russell A. Norris
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
Filamin-A
myxomatous valve disease
hematopoietic cells
macrophage
Online Access:http://www.mdpi.com/2308-3425/2/3/200

Internet

http://www.mdpi.com/2308-3425/2/3/200

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