Quantitative analysis of focused a-to-I RNA editing sites by ultra-high-throughput sequencing in psychiatric disorders.

A-to-I RNA editing is a post-transcriptional modification of single nucleotides in RNA by adenosine deamination, which thereby diversifies the gene products encoded in the genome. Thousands of potential RNA editing sites have been identified by recent studies (e.g. see Li et al, Science 2009); howev...

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Bibliographic Details
Main Authors: Hu Zhu, Daniel J Urban, Jared Blashka, Matthew T McPheeters, Wesley K Kroeze, Piotr Mieczkowski, James C Overholser, George J Jurjus, Lesa Dieter, Gouri J Mahajan, Grazyna Rajkowska, Zefeng Wang, Patrick F Sullivan, Craig A Stockmeier, Bryan L Roth
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3422315?pdf=render