Mutational concordance between primary and metastatic melanoma: a next-generation sequencing approach

Mutational concordance between primary and metastatic melanoma: a next-generation sequencing approach

Abstract Background Cutaneous malignant melanoma (CMM) is one of the most common skin cancers worldwide. Limited information is available in the current scientific literature on the concordance of genetic alterations between primary and metastatic CMM. In the present study, we performed next-generat...

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Main Authors: Antonella Manca, Panagiotis Paliogiannis, Maria Colombino, Milena Casula, Amelia Lissia, Gerardo Botti, Corrado Caracò, Paolo A. Ascierto, Maria Cristina Sini, Grazia Palomba, Marina Pisano, Melanoma Unit of Sassari (MUS), Italian Association for Cancer Research (AIRC) Study Group, Valentina Doneddu, Antonio Cossu, Giuseppe Palmieri, for the Italian Melanoma Intergroup (IMI)
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Journal of Translational Medicine
Subjects:
Skin
Cancer
Melanoma
BRAF
NRAS
Mutations
Online Access:http://link.springer.com/article/10.1186/s12967-019-2039-4

Internet

http://link.springer.com/article/10.1186/s12967-019-2039-4

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