An Age-Structured Model of HIV Latent Infection with Two Transmission Routes: Analysis and Optimal Control

In addition to direct virus infection of target cells, HIV can also be transferred from infected to uninfected cells (cell-to-cell transmission). These two routes might facilitate viral production and the establishment of the latent virus pool, which is considered as a major obstacle to HIV cure. We...

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Bibliographic Details
Main Authors: Chunyang Qin, Xia Wang, Libin Rong
Format: Article
Language:English
Published: Hindawi-Wiley 2020-01-01
Series:Complexity
Online Access:http://dx.doi.org/10.1155/2020/1890320