Association between polymorphism gene ABCB1, encodes glycoprotein P, and efficacy and safety profile of haloperidol in patients with alcohol addiction

Haloperidol is used in the practice of drug for relief of updating drives in patients suffering from a pathological attraction to alcohol, but the empirical selection of its dosage often leads to the development of patient adverse drug reactions. Synthesis of glycoprotein P, involved in the excretio...

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Bibliographic Details
Main Authors: M S Zastrozhin, K A Rizhikova, K B Mirzaev, Jh A Sozaeva, E A Grishina, D A Sychev, L M Savchenko, Yu Sh Gushina, S R Pahomov
Format: Article
Language:English
Published: Peoples’ Friendship University of Russia (RUDN University) 2017-12-01
Series:RUDN Journal of Medicine
Subjects:
Online Access:http://journals.rudn.ru/medicine/article/view/15225