Protein damage, ageing and age-related diseases

Ageing is considered as a snowballing phenotype of the accumulation of damaged dysfunctional or toxic proteins and silent mutations (polymorphisms) that sensitize relevant proteins to oxidative damage as inborn predispositions to age-related diseases. Ageing is not a disease, but it causes (or share...

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Bibliographic Details
Main Authors: Anita Krisko, Miroslav Radman
Format: Article
Language:English
Published: The Royal Society 2019-03-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.180249