Recanalization and reperfusion therapies of acute ischemic stroke: what have we learned, what are the major research questions, and where are we headed?

Two placebo-controlled trials have shown that early administration of intravenous recombinant tissue plasminogen activator (rt-PA) after ischemic stroke improves outcomes since 4.5h after symptoms onset; meanwhile another six trials cannot demonstrate it. We also know from the analysis of the pooled...

Full description

Bibliographic Details
Main Authors: Meritxell eGomis, Antoni eDávalos
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-11-01
Series:Frontiers in Neurology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fneur.2014.00226/full