Efficacy and Feasibility of the Epithelial Cell Adhesion Molecule (EpCAM) Immunomagnetic Cell Sorter for Studies of DNA Methylation in Colorectal Cancer

Efficacy and Feasibility of the Epithelial Cell Adhesion Molecule (EpCAM) Immunomagnetic Cell Sorter for Studies of DNA Methylation in Colorectal Cancer

The aim of this work was to assess the impact on measurements of methylation of a panel of four cancer gene promoters of purifying tumor cells from colorectal tissue samples using the epithelial cell adhesion molecule (EpCAM)-immunomagnetic cell enrichment approach. We observed that, on average, met...

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Bibliographic Details
Main Authors: Alessandra Failli, Annalisa Legitimo, Francesca Migheli, Fabio Coppedè, John C. Mathers, Roberto Spisni, Paolo Miccoli, Lucia Migliore, Rita Consolini
Format: Article
Language:English
Published: MDPI AG 2013-12-01
Series:International Journal of Molecular Sciences
Subjects:
DNA methylation
epigenetics
epithelial cell adhesion molecule (EpCAM)
immunomagnetic enrichment
colon cancer
pyrosequencing
Online Access:http://www.mdpi.com/1422-0067/15/1/44

Internet

http://www.mdpi.com/1422-0067/15/1/44

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