CD39+ Regulatory T Cells Attenuate Lipopolysaccharide-Induced Acute Lung Injury via Autophagy and the ERK/FOS Pathway

CD39+ Regulatory T Cells Attenuate Lipopolysaccharide-Induced Acute Lung Injury via Autophagy and the ERK/FOS Pathway

Acute respiratory distress syndrome (ARDS) is characterized by an uncontrollable cytokine storm, which is associated with high mortality due to lack of effective treatment. Regulatory T cells (Tregs) play an indispensable role in maintaining immune homeostasis and CD39 is considered as a functional...

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Bibliographic Details
Main Authors: Cen Chen, Xinying Li, Chuling Li, Jiajia Jin, Donghui Wang, Yuan Zhao, Yanli Gu, Meizi Chen, Suhua Zhu, Hongbing Liu, Tangfeng Lv, Fang Zhang, Yong Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Immunology
Subjects:
acute respiratory distress syndrome
CD39
regulatory T cells
acute lung injury
adoptive transfer
autography
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.602605/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.602605/full

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