Focal necrosis and disturbed myelination in the white matter of newborn infants: A tale of too much or too little oxygen

White matter disease in preterm infants comes along with focal destructions or with diffuse myelination disturbance. Recent experimental work with transgenic mice paves the way for a unifying molecular model for both types of brain injury, placing oxygen sensing by oligodendrocyte precursor cells at...

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Bibliographic Details
Main Authors: Sven eWellmann, Christoph eBührer, Thomas eSchmitz
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-01-01
Series:Frontiers in Pediatrics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fped.2014.00143/full