Ascorbic acid supports ex vivo generation of plasmacytoid dendritic cells from circulating hematopoietic stem cells

Ascorbic acid supports ex vivo generation of plasmacytoid dendritic cells from circulating hematopoietic stem cells

Plasmacytoid dendritic cells (pDCs) constitute a rare type of immune cell with multifaceted functions, but their potential use as a cell-based immunotherapy is challenged by the scarce cell numbers that can be extracted from blood. Here, we systematically investigate culture parameters for generatin...

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Bibliographic Details
Main Authors: Anders Laustsen, Renée M van der Sluis, Albert Gris-Oliver, Sabina Sánchez Hernández, Ena Cemalovic, Hai Q Tang, Lars Henning Pedersen, Niels Uldbjerg, Martin R Jakobsen, Rasmus O Bak
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-09-01
Series:eLife
Subjects:
ascorbic acid
plasmacytoid
pDC
dendritic cells
hematopoietic stem cells
vitamin c
Online Access:https://elifesciences.org/articles/65528

Internet

https://elifesciences.org/articles/65528

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