New Perspectives on Rodent Models of Advanced Paternal Age: Relevance to Autism

Offspring of older fathers have an increased risk of various adverse health outcomes, including autism and schizophrenia. With respect to biological mechanisms for this association, there are many more germline cell divisions in the life history of a sperm relative to that of an oocyte. This leads t...

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Bibliographic Details
Main Authors: Claire J Foldi, Darryl W Eyles, Traute eFlatscher-Bader, John J McGrath, Thomas H J Burne
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-06-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
rat
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2011.00032/full