Guidelines for the pharmacological acute treatment of major depression: conflicts with current evidence as demonstrated with the German S3-guidelines

Abstract Several international guidelines for the acute treatment of moderate to severe unipolar depression recommend a first-line treatment with antidepressants (AD). This is based on the assumption that AD obviously outperform placebo, at least in the case of severe depression. The efficacy of AD...

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Bibliographic Details
Main Authors: Martin Plöderl, Michael P. Hengartner
Format: Article
Language:English
Published: BMC 2019-09-01
Series:BMC Psychiatry
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12888-019-2230-4