Web-based design and analysis tools for CRISPR base editing

Web-based design and analysis tools for CRISPR base editing

Abstract Background As a result of its simplicity and high efficiency, the CRISPR-Cas system has been widely used as a genome editing tool. Recently, CRISPR base editors, which consist of deactivated Cas9 (dCas9) or Cas9 nickase (nCas9) linked with a cytidine or a guanine deaminase, have been develo...

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Bibliographic Details
Main Authors: Gue-Ho Hwang, Jeongbin Park, Kayeong Lim, Sunghyun Kim, Jihyeon Yu, Eunchong Yu, Sang-Tae Kim, Roland Eils, Jin-Soo Kim, Sangsu Bae
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Bioinformatics
Subjects:
CRISPR
Base editing
Web-based tool
Genome editing
NGS analysis
Online Access:http://link.springer.com/article/10.1186/s12859-018-2585-4

Internet

http://link.springer.com/article/10.1186/s12859-018-2585-4

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