Proteasomal and autophagic degradative activities in spinal and bulbar muscular atrophy

Proteasomal and autophagic degradative activities in spinal and bulbar muscular atrophy

Spinal and bulbar muscular atrophy (SBMA or Kennedy's disease) is a fatal neurodegenerative disease characterized by the selective loss of motor neurons in the bulbar region of the brain and in the anterior horns of the spinal cord. The disease has been associated to an expansion of a CAG tripl...

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Bibliographic Details
Main Authors: Paola Rusmini, Elena Bolzoni, Valeria Crippa, Elisa Onesto, Daniela Sau, Mariarita Galbiati, Margherita Piccolella, Angelo Poletti
Format: Article
Language:English
Published: Elsevier 2010-11-01
Series:Neurobiology of Disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996110002123

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http://www.sciencedirect.com/science/article/pii/S0969996110002123

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