Cholesterol in the Viral Membrane is a Molecular Switch Governing HIV‐1 Env Clustering

Cholesterol in the Viral Membrane is a Molecular Switch Governing HIV‐1 Env Clustering

Abstract HIV‐1 entry requires the redistribution of envelope glycoproteins (Env) into a cluster and the presence of cholesterol (chol) in the viral membrane. However, the molecular mechanisms underlying the specific role of chol in infectivity and the driving force behind Env clustering remain unkno...

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Bibliographic Details
Main Authors: Jon Ander Nieto‐Garai, Aroa Arboleya, Sara Otaegi, Jakub Chojnacki, Josefina Casas, Gemma Fabriàs, F‐Xabier Contreras, Hans‐Georg Kräusslich, Maier Lorizate
Format: Article
Language:English
Published: Wiley 2021-02-01
Series:Advanced Science
Subjects:
cholesterol
Env clustering
gp41 cytoplasmic tails
HIV‐1
protein–lipid interactions
Online Access:https://doi.org/10.1002/advs.202003468

Internet

https://doi.org/10.1002/advs.202003468

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