Cholesterol in the Viral Membrane is a Molecular Switch Governing HIV‐1 Env Clustering
Abstract HIV‐1 entry requires the redistribution of envelope glycoproteins (Env) into a cluster and the presence of cholesterol (chol) in the viral membrane. However, the molecular mechanisms underlying the specific role of chol in infectivity and the driving force behind Env clustering remain unkno...
Main Authors: | Jon Ander Nieto‐Garai, Aroa Arboleya, Sara Otaegi, Jakub Chojnacki, Josefina Casas, Gemma Fabriàs, F‐Xabier Contreras, Hans‐Georg Kräusslich, Maier Lorizate |
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Format: | Article |
Language: | English |
Published: |
Wiley
2021-02-01
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Series: | Advanced Science |
Subjects: | |
Online Access: | https://doi.org/10.1002/advs.202003468 |
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