Metabolomic Study of High-Fat Diet-Induced Obese (DIO) and DIO Plus CCl<sub>4</sub>-Induced NASH Mice and the Effect of Obeticholic Acid

The pathophysiology of nonalcoholic fatty liver disease (NAFLD) is a complex process involving metabolic and inflammatory changes in livers and other organs, but the pathogenesis is still not well clarified. Two mouse models were established to study metabolic alteration of nonalcoholic fatty liver...

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Bibliographic Details
Main Authors: Nanlin Zhu, Suling Huang, Qingli Zhang, Zhuohui Zhao, Hui Qu, Mengmeng Ning, Ying Leng, Jia Liu
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/11/6/374