The fibrinolytic system facilitates tumor cell migration across the blood-brain barrier in experimental melanoma brain metastasis

<p>Abstract</p> <p>Background</p> <p>Patients with metastatic tumors to the brain have a very poor prognosis. Increased metastatic potential has been associated with the fibrinolytic system. We investigated the role of the fibrinolytic enzyme plasmin in tumor cell migra...

Full description

Bibliographic Details
Main Authors: Bronson Roderick T, Stins Monique F, Lin Tina, Zhuge Yuzheng, Perides George, Wu Julian K
Format: Article
Language:English
Published: BMC 2006-03-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/6/56