The Role of PAS Kinase in PASsing the Glucose Signal

PAS kinase is an evolutionarily conserved nutrient responsive protein kinase that regulates glucose homeostasis. Mammalian PAS kinase is activated by glucose in pancreatic beta cells, and knockout mice are protected from obesity, liver triglyceride accumulation, and insulin resistance when fed a hig...

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Bibliographic Details
Main Authors: Julianne H. Grose, Jared Rutter
Format: Article
Language:English
Published: MDPI AG 2010-06-01
Series:Sensors
Subjects:
Online Access:http://www.mdpi.com/1424-8220/10/6/5668/