The Role of PAS Kinase in PASsing the Glucose Signal
PAS kinase is an evolutionarily conserved nutrient responsive protein kinase that regulates glucose homeostasis. Mammalian PAS kinase is activated by glucose in pancreatic beta cells, and knockout mice are protected from obesity, liver triglyceride accumulation, and insulin resistance when fed a hig...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2010-06-01
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Series: | Sensors |
Subjects: | |
Online Access: | http://www.mdpi.com/1424-8220/10/6/5668/ |