NADPH oxidase 2-derived reactive oxygen species signal contributes to bradykinin-induced matrix metalloproteinase-9 expression and cell migration in brain astrocytes

NADPH oxidase 2-derived reactive oxygen species signal contributes to bradykinin-induced matrix metalloproteinase-9 expression and cell migration in brain astrocytes

<p>Abstract</p> <p>Background</p> <p>Matrix metalloproteinase-9 (MMP-9) plays a crucial role in pathological processes of brain inflammation, injury, and neurodegeneration. Moreover, bradykinin (BK) induces the expression of several inflammatory proteins in brain astroc...

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Bibliographic Details
Main Authors: Lin Chih-Chung, Hsieh Hsi-Lung, Shih Ruey-Horng, Chi Pei-Ling, Cheng Shin-Ei, Chen Jin-Chung, Yang Chuen-Mao
Format: Article
Language:English
Published: BMC 2012-11-01
Series:Cell Communication and Signaling
Subjects:
Brain inflammation
Astrocytes
Bradykinin
Matrix metalloproteinase-9
NADPH oxidase
Reactive oxygen species
Online Access:http://www.biosignaling.com/content/10/1/35

Internet

http://www.biosignaling.com/content/10/1/35

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