Mibefradil reduces blood glucose concentration in db/db mice

Mibefradil reduces blood glucose concentration in db/db mice

OBJECTIVE: Numerous recent studies suggest that abnormal intracellular calcium concentration ([Ca2+]i) is a common defect in diabetic animal models and patients. Abnormal calcium handling is an important mechanism in the defective pancreatic β-cell function in type 2 diabetes. T-type Ca2+ channel an...

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Bibliographic Details
Main Authors: Yujie Lu, Min Long, Shiwen Zhou, Zihui Xu, Fuquan Hu, Ming Li
Format: Article
Language:English
Published: Faculdade de Medicina / USP 2014-01-01
Series:Clinics
Subjects:
Diabetes Mellitus
Hypoglycemic Effect
Insulin
Food Intake
T-type Ca2+ Channel Antagonist
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322014000100061&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322014000100061&lng=en&tlng=en

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