Expression of Vitamin D Receptor (VDR) Positively Correlates with Survival of Urothelial Bladder Cancer Patients

Vitamin D3 shows tumoristatic and anticancer effects by acting through the vitamin D receptor (VDR), while hydroxylation of 25-hydroxyvitamin D3 at position 1α by CYP27B1 is an essential step in its activation. The expression of both the VDR and CYP27B1 has been found in many normal and cancer tiss...

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Bibliographic Details
Main Authors: Wojciech Jóźwicki, Anna A. Brożyna, Jerzy Siekiera, Andrzej T. Slominski
Format: Article
Language:English
Published: MDPI AG 2015-10-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/16/10/24369