Insights from the reconstitution of the divergent outer kinetochore of Drosophila melanogaster

Accurate chromosome segregation during mitosis and meiosis is crucial for cellular and organismal viability. Kinetochores connect chromosomes with spindle microtubules and are essential for chromosome segregation. These large protein scaffolds emerge from the centromere, a specialized region of the...

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Bibliographic Details
Main Authors: Yahui Liu, Arsen Petrovic, Pascaline Rombaut, Shyamal Mosalaganti, Jenny Keller, Stefan Raunser, Franz Herzog, Andrea Musacchio
Format: Article
Language:English
Published: The Royal Society 2016-01-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.150236