Global profiling in vestibular schwannomas shows critical deregulation of microRNAs and upregulation in those included in chromosomal region 14q32.

Global profiling in vestibular schwannomas shows critical deregulation of microRNAs and upregulation in those included in chromosomal region 14q32.

BACKGROUND: Vestibular schwannomas are benign tumors that arise from Schwann cells in the VIII cranial pair and usually present NF2 gene mutations and/or loss of heterozygosity on chromosome 22q. Deregulation has also been found in several genes, such as ERBB2 and NRG1. MicroRNAs are non-coding RNAs...

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Bibliographic Details
Main Authors: Miguel Torres-Martin, Luis Lassaletta, Jose M de Campos, Alberto Isla, Javier Gavilan, Giovanny R Pinto, Rommel R Burbano, Farida Latif, Barbara Melendez, Javier S Castresana, Juan A Rey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3679163?pdf=render

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http://europepmc.org/articles/PMC3679163?pdf=render

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