Global profiling in vestibular schwannomas shows critical deregulation of microRNAs and upregulation in those included in chromosomal region 14q32.
BACKGROUND: Vestibular schwannomas are benign tumors that arise from Schwann cells in the VIII cranial pair and usually present NF2 gene mutations and/or loss of heterozygosity on chromosome 22q. Deregulation has also been found in several genes, such as ERBB2 and NRG1. MicroRNAs are non-coding RNAs...
Main Authors: | Miguel Torres-Martin, Luis Lassaletta, Jose M de Campos, Alberto Isla, Javier Gavilan, Giovanny R Pinto, Rommel R Burbano, Farida Latif, Barbara Melendez, Javier S Castresana, Juan A Rey |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3679163?pdf=render |
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