Improved Clearance during Treatment of HPV-Positive Head and Neck Cancer through mTOR Inhibition

Human papillomavirus (HPV)-related head and neck squamous cell carcinoma (HNSCC) incidence is increasing at a near epidemic rate. We investigated whether the mammalian (or mechanistic) target of rapamycin (mTOR) inhibitor, rapamycin, can be used as a concurrent agent to standard-of-care cisplatin/r...

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Bibliographic Details
Main Authors: Joseph D. Coppock, Bryant G. Wieking, Alfredo A. Molinolo, J. Silvio Gutkind, W. Keith Miskimins, John H. Lee
Format: Article
Language:English
Published: Elsevier 2013-06-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558613801352