Preoperative myocardial expression of E3 ubiquitin ligases in aortic stenosis patients undergoing valve replacement and their association to postoperative hypertrophy

Currently, aortic valve replacement is the only treatment capable of relieving left ventricle pressure overload in patients with severe aortic stenosis. It aims to improve cardiac function and revert hypertrophy, by triggering myocardial reverse remodeling. Despite immediately relieving afterload, r...

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Bibliographic Details
Main Authors: Fábio Trindade, Francisca Saraiva, Simon Keane, Adelino Leite-Moreira, Rui Vitorino, Homa Tajsharghi, Inês Falcão-Pires, Cécile Oury
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500680/?tool=EBI