Somatic Trp53 mutations differentially drive breast cancer and evolution of metastases

Somatic Trp53 mutations differentially drive breast cancer and evolution of metastases

Mutations in TP53 gene are very common in cancer development. Here the authors take advantage of murine models to show that somatic Trp53 mutations differentially drive breast cancer and evolution of metastases.

Bibliographic Details
Main Authors: Yun Zhang, Shunbin Xiong, Bin Liu, Vinod Pant, Francis Celii, Gilda Chau, Ana C. Elizondo-Fraire, Peirong Yang, Mingjian James You, Adel K. El-Naggar, Nicholas E. Navin, Guillermina Lozano
Format: Article
Language:English
Published: Nature Publishing Group 2018-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-06146-9

Internet

https://doi.org/10.1038/s41467-018-06146-9

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