Breast Cancer Proteins PALB2 and BRCA2 Stimulate Polymerase η in Recombination-Associated DNA Synthesis at Blocked Replication Forks

One envisioned function of homologous recombination (HR) is to find a template for DNA synthesis from the resected 3′-OH molecules that occur during double-strand break (DSB) repair at collapsed replication forks. However, the interplay between DNA synthesis and HR remains poorly understood in highe...

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Bibliographic Details
Main Authors: Rémi Buisson, Joshi Niraj, Joris Pauty, Ranjan Maity, Weixing Zhao, Yan Coulombe, Patrick Sung, Jean-Yves Masson
Format: Article
Language:English
Published: Elsevier 2014-02-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714000102