Role of 3-Mercaptopyruvate Sulfurtransferase in the Regulation of Proliferation and Cellular Bioenergetics in Human Down Syndrome Fibroblasts

Down syndrome (trisomy of human chromosome 21) is a common genetic disorder. Overproduction of the gaseous mediator hydrogen sulfide (H<sub>2</sub>S) has been implicated in the pathogenesis of neurological and metabolic deficits associated with Down syndrome. Several lines of data indica...

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Bibliographic Details
Main Authors: Theodora Panagaki, Elisa B. Randi, Csaba Szabo
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Biomolecules
Subjects:
ATP
Online Access:https://www.mdpi.com/2218-273X/10/4/653