Dysregulation of EMT Drives the Progression to Clinically Aggressive Sarcomatoid Bladder Cancer

Dysregulation of EMT Drives the Progression to Clinically Aggressive Sarcomatoid Bladder Cancer

Summary: Sarcomatoid urothelial bladder cancer (SARC) displays a high propensity for distant metastasis and is associated with short survival. We report a comprehensive genomic analysis of 28 cases of SARC and 84 cases of conventional urothelial carcinoma (UC), with the TCGA cohort of 408 muscle-inv...

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Main Authors: Charles C. Guo, Tadeusz Majewski, Li Zhang, Hui Yao, Jolanta Bondaruk, Yan Wang, Shizhen Zhang, Ziqiao Wang, June Goo Lee, Sangkyou Lee, David Cogdell, Miao Zhang, Peng Wei, H. Barton Grossman, Ashish Kamat, Jonathan James Duplisea, James Edward Ferguson, III, He Huang, Vipulkumar Dadhania, Jianjun Gao, Colin Dinney, John N. Weinstein, Keith Baggerly, David McConkey, Bogdan Czerniak
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719305212

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http://www.sciencedirect.com/science/article/pii/S2211124719305212

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