Elevation of plasma tRNA fragments as a promising biomarker for liver fibrosis in nonalcoholic fatty liver disease

Abstract Fibrotic tissue remodelling in nonalcoholic fatty liver disease (NAFLD) will probably emerge as the leading cause of end-stage liver disease in the coming decades, but the ability to diagnose liver fibrosis in NAFLD patients noninvasively is limited. The abnormal expression of tRNA-derived...

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Bibliographic Details
Main Authors: Peng Huang, Biao Tu, Hui-jun Liao, Fei-zhou Huang, Zhen-zhou Li, Kuang-ye Zhu, Feng Dai, Huai-zheng Liu, Tian-yi Zhang, Chuan-zheng Sun
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-85421-0