Carbon Nanotubes and Short Cytosine-Rich Telomeric DNA Oligomeres as Platforms for Controlled Release of Doxorubicin—A Molecular Dynamics Study

Carbon Nanotubes and Short Cytosine-Rich Telomeric DNA Oligomeres as Platforms for Controlled Release of Doxorubicin—A Molecular Dynamics Study

This work deals with molecular dynamics analysis of properties of systems composed of carbon nanotubes and short telomeric DNA strands able to fold into i-motif structures at slightly acidic pH conditions. The studies are focused on possible application of such constructs as pH-controlled drug deliv...

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Bibliographic Details
Main Authors: Pawel Wolski, Krzysztof Nieszporek, and Tomasz Panczyk
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:International Journal of Molecular Sciences
Subjects:
i-motif
carbon nanotube
drug delivery
doxorubicin
molecular dynamics
force field
Online Access:https://www.mdpi.com/1422-0067/21/10/3619

Internet

https://www.mdpi.com/1422-0067/21/10/3619

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