PRMT6 mediates inflammation via activation of the NF-κB/ p65 pathway on a cigarette smoke extract-induced murine emphysema model

Introduction Smoke-driven lung inflammation is considered to be the major pathophysiology mechanism of Chronic Obstructive Pulmonary Disease (COPD)/ emphysema. Protein arginine methyltransferase 6 (PRMT6) is a key epigenetic enzyme, which is related to protecting the tri-methylation of H3K4 (H3K4me3...

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Bibliographic Details
Main Authors: Xue He, Tiao Li, Lijuan Luo, Huihui Zeng, Yan Chen, Shan Cai
Format: Article
Language:English
Published: European Publishing 2020-02-01
Series:Tobacco Induced Diseases
Subjects:
Online Access:http://www.journalssystem.com/tid/PRMT6-mediates-inflammation-via-the-activation-of-NF-B-p65-pathway-on-cigarette-smoke,116413,0,2.html