Structural Basis for Molecular Discrimination by a 3′,3′-cGAMP Sensing Riboswitch

Structural Basis for Molecular Discrimination by a 3′,3′-cGAMP Sensing Riboswitch

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Cyclic dinucleotides are second messengers that target the adaptor STING and stimulate the innate immune response in mammals. Besides protein receptors, there are bacterial riboswitches that selectively recognize cyclic dinucleotides. We recently discovered a natural riboswitch that targets 3′,3′-cG...

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Bibliographic Details
Main Authors: Aiming Ren, Xin C. Wang, Colleen A. Kellenberger, Kanagalaghatta R. Rajashankar, Roger A. Jones, Ming C. Hammond, Dinshaw J. Patel
Format: Article
Language:English
Published: Elsevier 2015-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715002466

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http://www.sciencedirect.com/science/article/pii/S2211124715002466

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