Structural Basis for Molecular Discrimination by a 3′,3′-cGAMP Sensing Riboswitch
Cyclic dinucleotides are second messengers that target the adaptor STING and stimulate the innate immune response in mammals. Besides protein receptors, there are bacterial riboswitches that selectively recognize cyclic dinucleotides. We recently discovered a natural riboswitch that targets 3′,3′-cG...
Main Authors: | Aiming Ren, Xin C. Wang, Colleen A. Kellenberger, Kanagalaghatta R. Rajashankar, Roger A. Jones, Ming C. Hammond, Dinshaw J. Patel |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2015-04-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124715002466 |
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