Genetic and Chemical Screenings Identify HDAC3 as a Key Regulator in Hepatic Differentiation of Human Pluripotent Stem Cells

Genetic and Chemical Screenings Identify HDAC3 as a Key Regulator in Hepatic Differentiation of Human Pluripotent Stem Cells

Summary: Hepatocyte-like cells (HLCs) derived from human pluripotent stem cells (hPSCs) offer a promising cell resource for disease modeling and transplantation. However, differentiated HLCs exhibit an immature phenotype and comprise a heterogeneous population. Thus, a better understanding of HLC di...

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Bibliographic Details
Main Authors: Shuang Li, Mushan Li, Xiaojian Liu, Yuanyuan Yang, Yuda Wei, Yanhao Chen, Yan Qiu, Tingting Zhou, Zhuanghui Feng, Danjun Ma, Jing Fang, Hao Ying, Hui Wang, Kiran Musunuru, Zhen Shao, Yongxu Zhao, Qiurong Ding
Format: Article
Language:English
Published: Elsevier 2018-07-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671118302182

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http://www.sciencedirect.com/science/article/pii/S2213671118302182

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