A Synthesized Glucocorticoid- Induced Leucine Zipper Peptide Inhibits Retinal Müller Cell Gliosis

A Synthesized Glucocorticoid- Induced Leucine Zipper Peptide Inhibits Retinal Müller Cell Gliosis

Purpose: The anti-inflammatory activities of protein glucocorticoid-induced leucine zipper (GILZ) have been demonstrated in vivo and in vitro. Here, we examined the potential effect of a synthetic peptide derived from the leucine zipper motif and proline-rich region of GILZ on suppressing inflammato...

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Bibliographic Details
Main Authors: Ruiping Gu, Xinyi Ding, Wenyi Tang, Boya Lei, Chen Jiang, Gezhi Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Pharmacology
Subjects:
synthetic glucocorticoid-induced leucine zipper peptide
Müller cell
gliosis
NF-κB p65
LPS
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2018.00331/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2018.00331/full

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